Cyto- and histometry in histological sections of colon carcinoma: method
Karsten Rodenacker,
Gsf-lnstitut für Strahlenschutz, Labor für biomedizinische Bildanalyse
Michaela Aubele,
Gsf-lnstitut für Strahlenschutz, Labor für biomedizinische Bildanalyse
Georg Burger,
Gsf-lnstitut für Strahlenschutz, Labor für biomedizinische Bildanalyse
Peter Gais,
Gsf-lnstitut für Strahlenschutz, Labor für biomedizinische Bildanalyse
Uta Jütting,
Gsf-lnstitut für Strahlenschutz, Labor für biomedizinische Bildanalyse
Wolfgang Gössner,
Gsf-lnstitut für Pathologie, Ingolstädter Landstr. 1, D-8042 Neuherberg, GDR
Martin Oberholzer,
lnstitut für Pathologie der Universität Basel, CH-4003 Basel, Switzerland
Abstract
Histological sections from colon carcinoma were evaluated by quantitative TV-microscopy. As a first step the nuclear profiles were digitized, segmented and measured. Besides classical cytometrical parameters like several global textural features, the fine structure of eu- and heterochromatin distribution was measured in terms of arrangement and neighbourhood relationship.
The resulting features are related to corresponding pathological diagnosis. As an example it is shown, that the existence of metastases may be correlated with features of the nuclear chromatin distribution.
Keywords : cytometry, graph theory, histometry, image analysis
Para citar este artículo
Karsten Rodenacker, Michaela Aubele, Georg Burger, Peter Gais, Uta Jütting, Wolfgang Gössner & Martin Oberholzer, «Cyto- and histometry in histological sections of colon carcinoma: method», Acta Stereologica [En ligne], Volume 9 (1990), Number 2 - Proceedings of the seventh workshop on quantitative image analysis - Freiburg 90 - Dec. 1990, 197-203 URL : https://popups.uliege.be/0351-580x/index.php?id=2880.