Acta Stereologica Acta Stereologica -  Volume 13 (1994)  Number 1 - Proceedings of the sixth European congress for stereology - Part two - May 1994 

Direct stereological estimation of 3-D connectivity density in human iliac cancellous bone: the effect of age and sex

Thomas A. Youngs
Department of Bone Metabolism, Rhone-Poulene Rorer Central Research, Collegeville, Pa, USA, Institute of Anatomy, Departement of Connective Tissue Biology, University of Aarhus and Stereological Research Laboratory, University of Aarhus, Århus, Denmark
Rogely W. Boyce
Department of Bone Metabolism, Rhone-Poulene Rorer Central Research, Collegeville, Pa, USA, Institute of Anatomy, Departement of Connective Tissue Biology, University of Aarhus and Stereological Research Laboratory, University of Aarhus, Århus, Denmark
Lis Mosekilde
Department of Bone Metabolism, Rhone-Poulene Rorer Central Research, Collegeville, Pa, USA, Institute of Anatomy, Departement of Connective Tissue Biology, University of Aarhus and Stereological Research Laboratory, University of Aarhus, Århus, Denmark
Charlotte H. Søgaard
Department of Bone Metabolism, Rhone-Poulene Rorer Central Research, Collegeville, Pa, USA, Institute of Anatomy, Departement of Connective Tissue Biology, University of Aarhus and Stereological Research Laboratory, University of Aarhus, Århus, Denmark
Caroline L. Paddock
Department of Bone Metabolism, Rhone-Poulene Rorer Central Research, Collegeville, Pa, USA, Institute of Anatomy, Departement of Connective Tissue Biology, University of Aarhus and Stereological Research Laboratory, University of Aarhus, Århus, Denmark
Hans Jørgen G. Gundersen
Department of Bone Metabolism, Rhone-Poulene Rorer Central Research, Collegeville, Pa, USA, Institute of Anatomy, Departement of Connective Tissue Biology, University of Aarhus and Stereological Research Laboratory, University of Aarhus, Århus, Denmark

Abstract

The use of a new, direct estimator of 3-D connectivity in arbitrary networks, the ConnEulor, based on the disector-principle is illustrated in a series of iliac crest bone necropsies. To obtain an unbiased estimate of connectivity or “trabecular number” takes about 1 hour per specimen.

A rather pronounced relation between connectivity and age was seen in females, it corresponds to a halving of trabecular number over ~50 years. No such relation was observed in males. No correlation obtained between connectivity and trabecular volume density.

Keywords : age, bone, connectivity, sex, stereology, trabeculae

To cite this article

Thomas A. Youngs, Rogely W. Boyce, Lis Mosekilde, Charlotte H. Søgaard, Caroline L. Paddock & Hans Jørgen G. Gundersen, «Direct stereological estimation of 3-D connectivity density in human iliac cancellous bone: the effect of age and sex», Acta Stereologica [En ligne], Volume 13 (1994), Number 1 - Proceedings of the sixth European congress for stereology - Part two - May 1994, 55-60 URL : https://popups.ulg.ac.be/0351-580x/index.php?id=996.