Acta Stereologica

0351-580X

 

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Thomas A. Youngs, Rogely W. Boyce, Lis Mosekilde, Charlotte H. Søgaard, Caroline L. Paddock & Hans Jørgen G. Gundersen

Direct stereological estimation of 3-D connectivity density in human iliac cancellous bone: the effect of age and sex

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Abstract

The use of a new, direct estimator of 3-D connectivity in arbitrary networks, the ConnEulor, based on the disector-principle is illustrated in a series of iliac crest bone necropsies. To obtain an unbiased estimate of connectivity or “trabecular number” takes about 1 hour per specimen.

A rather pronounced relation between connectivity and age was seen in females, it corresponds to a halving of trabecular number over ~50 years. No such relation was observed in males. No correlation obtained between connectivity and trabecular volume density.

Keywords : age, bone, connectivity, sex, stereology, trabeculae

To cite this article

Thomas A. Youngs, Rogely W. Boyce, Lis Mosekilde, Charlotte H. Søgaard, Caroline L. Paddock & Hans Jørgen G. Gundersen, «Direct stereological estimation of 3-D connectivity density in human iliac cancellous bone: the effect of age and sex», Acta Stereologica [En ligne], Volume 13 (1994), Number 1 - Proceedings of the sixth European congress for stereology - Part two - May 1994, 55-60 URL : https://popups.ulg.ac.be/0351-580x/index.php?id=996.

About: Thomas A. Youngs

Department of Bone Metabolism, Rhone-Poulene Rorer Central Research, Collegeville, Pa, USA, Institute of Anatomy, Departement of Connective Tissue Biology, University of Aarhus and Stereological Research Laboratory, University of Aarhus, Århus, Denmark

About: Rogely W. Boyce

Department of Bone Metabolism, Rhone-Poulene Rorer Central Research, Collegeville, Pa, USA, Institute of Anatomy, Departement of Connective Tissue Biology, University of Aarhus and Stereological Research Laboratory, University of Aarhus, Århus, Denmark

About: Lis Mosekilde

Department of Bone Metabolism, Rhone-Poulene Rorer Central Research, Collegeville, Pa, USA, Institute of Anatomy, Departement of Connective Tissue Biology, University of Aarhus and Stereological Research Laboratory, University of Aarhus, Århus, Denmark

About: Charlotte H. Søgaard

Department of Bone Metabolism, Rhone-Poulene Rorer Central Research, Collegeville, Pa, USA, Institute of Anatomy, Departement of Connective Tissue Biology, University of Aarhus and Stereological Research Laboratory, University of Aarhus, Århus, Denmark

About: Caroline L. Paddock

Department of Bone Metabolism, Rhone-Poulene Rorer Central Research, Collegeville, Pa, USA, Institute of Anatomy, Departement of Connective Tissue Biology, University of Aarhus and Stereological Research Laboratory, University of Aarhus, Århus, Denmark

About: Hans Jørgen G. Gundersen

Department of Bone Metabolism, Rhone-Poulene Rorer Central Research, Collegeville, Pa, USA, Institute of Anatomy, Departement of Connective Tissue Biology, University of Aarhus and Stereological Research Laboratory, University of Aarhus, Århus, Denmark