Using mathematical morphology to eliminate debris and aggregates before DNA ploidy measurement of solid tumours

Christophe Boudry; Paulette Herlin; Michel Coster; Jean-Louis Chermant; Brigitte Sola; Michel Henry-Amar

Acta Stereologica

0351-580X

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Christophe Boudry, Paulette Herlin, Michel Coster, Jean-Louis Chermant, Brigitte Sola & Michel Henry-Amar

Using mathematical morphology to eliminate debris and aggregates before DNA ploidy measurement of solid tumours

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Abstract

Software strictly dedicated to DNA tumour measurement was previously developed, providing an automatic sorting of cellular elements based on a multiparametric analysis. Prospective research now focuses on the simplification of the sorting procedure. Mathematical morphology was used for pre-elimination of debris and aggregates. The results were compared to those obtained with multiparametric analysis. It is concluded that mathematical morphology is a promising tool.

Keywords : aggregates, debris, DNA ploidy measurement, mathematical morphology, solid tumours

Om dit artikel te citeren:

Christophe Boudry, Paulette Herlin, Michel Coster, Jean-Louis Chermant, Brigitte Sola & Michel Henry-Amar, «Using mathematical morphology to eliminate debris and aggregates before DNA ploidy measurement of solid tumours», Acta Stereologica [En ligne], Volume 14 (1995), Number 2 - Quantitative image analysis - Nov. 1995, 121-128 URL : https://popups.ulg.ac.be/0351-580x/index.php?id=745.

Over : Christophe Boudry

LERMAT, URA CNRS 1317, ISMRA, 14050 Caen Cedex, France; Centre F. Baclesse, Service d’Anatomie Pathologique, 14021 Caen, France; Université de Caen, URA CNRS 1829, 14074 Caen, France