Acta Stereologica Acta Stereologica -  Volume 3 (1984)  Number 1 - May 1984 

A stereological investigation of the rat exocrine pancreas after long-term alcohol consumption

Vesna Koko
Institute for Medical Research Bulevar JNA 10, 11000 Beograd, Yugoslavia
Ana Laban
Institute for Medical Research Bulevar JNA 10, 11000 Beograd, Yugoslavia
Jelena Radovanović
Institute for Medical Research Bulevar JNA 10, 11000 Beograd, Yugoslavia
Milosav Ristić
Institute for Medical Research Bulevar JNA 10, 11000 Beograd, Yugoslavia

Abstract

A stereological analysis of the rat exocrine pancreas after 6 months of ethanol ingestion was carried out. Thirty male Wistar rats, aged two months at the beginning of the experiment, were divided into two groups. Both of them received a standard laboratory diet. The control group of animals was offered drinking water ad libitum. The experimental group of animals was drinking an ethanol solution. Weibel's multipurpose test system was used to determine the volume density of some exocrine pancreas components.

The results presented show that long-term alcohol ingestion decreased the relative density of the acini and increased the relative volume density of intralobular ducts, connective tissue fibres and artificial spaces. The mean radius of the acini was decreased, but the mean radius of the cell nuclei was increased.

To cite this article

Vesna Koko, Ana Laban, Jelena Radovanović & Milosav Ristić, «A stereological investigation of the rat exocrine pancreas after long-term alcohol consumption», Acta Stereologica [En ligne], Volume 3 (1984), Number 1 - May 1984, 101-108 URL : https://popups.ulg.ac.be/0351-580x/index.php?id=3981.