Acta Stereologica

0351-580X

 

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Veli-Matti Kosma, Kalevi Selkäinaho, Yrjö Collan, Kari Syrjänen, Marja-Leena Aalto & Anders Seppä

Grading of postcapillary venules in lymph nodes: observer variation and reproducibility in subjective estimation and morphometric measurements

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Abstract

We wanted to estimate variation and reproducibility in grading and in morphometric measurements of postcapillary venules. Five pathologists measured 100 postcapillary venules from 20 axillary lymph nodes by subjective and morphometric means. Range of variation was similar in subjective and morphometric measurements. The correlation coefficients between subjective and morphometric measurements varied from 0.62 to 0.93. On subjective grading of the individual postcapillary venules the kappa coefficient was 0.50 (90% limits: 0.40-0.56). On morphometry ICC was 0.74 (0.70-0.78). On morphometric measurements of individual lymph nodes ICC was 0.82. The results show that grading and morphometric measurements are very similar in respect to variability and reproducibility in this kind of experiment.

To cite this article

Veli-Matti Kosma, Kalevi Selkäinaho, Yrjö Collan, Kari Syrjänen, Marja-Leena Aalto & Anders Seppä, «Grading of postcapillary venules in lymph nodes: observer variation and reproducibility in subjective estimation and morphometric measurements», Acta Stereologica [En ligne], Volume 3 (1984), Number 1 - May 1984, 39-42 URL : https://popups.ulg.ac.be/0351-580x/index.php?id=3921.

About: Veli-Matti Kosma

Department of Pathology, University of Kuopio, P.O.Box 6, SF 70211 Kuopio 21, Finland

About: Kalevi Selkäinaho

Department of Applied Mathematics, University of Kuopio, P.O.Box 6, SF 70211 Kuopio 21, Finland

About: Yrjö Collan

Department of Pathology, University of Kuopio, P.O.Box 6, SF 70211 Kuopio 21, Finland

About: Kari Syrjänen

Department of Pathology, University of Kuopio, P.O.Box 6, SF 70211 Kuopio 21, Finland

About: Marja-Leena Aalto

Department of Pathology, University of Kuopio, P.O.Box 6, SF 70211 Kuopio 21, Finland

About: Anders Seppä

Department of Pathology, University of Kuopio, P.O.Box 6, SF 70211 Kuopio 21, Finland