Acta Stereologica

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Vladimír Semecký, Andrea Gojová, Petr Nachtigal, Kamila Langrová & Viktor Beneš

Stereological analysis of pathological changes in the blood-vessel wall after experimental induction of hypercholesterolemia

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Abstract

The microarchitecture of blood-vessels of elastic type (aorta abdominalis, arteria iliaca) was observed at rabbits after a long time diet enriched by cholesterol. Using optical microscopy pathological changes along the blood-vessel were studied. Using the Cavalieri principle the volume of atherosclerotic lesions is estimated and the precision of estimators investigated. The permeability of blood-vessels is quantified by the ratio of lumen section area without and with plaques from transverse histological sections.

Keywords : atherosclerotic plaques, blood vessel wall, Cavalieri principle, stereological methods

Pour citer cet article

Vladimír Semecký, Andrea Gojová, Petr Nachtigal, Kamila Langrová & Viktor Beneš, «Stereological analysis of pathological changes in the blood-vessel wall after experimental induction of hypercholesterolemia», Acta Stereologica [En ligne], Volume 17 (1998), Number 3 - Dec. 1998, 383-388 URL : https://popups.ulg.ac.be/0351-580x/index.php?id=364.

A propos de : Vladimír Semecký

Charles University, Pharmaceutic Faculty, Dept. of Biological and Medical Sciences, Heyrovského 1203, 50005 Hradec Králové, Czech Republic

A propos de : Andrea Gojová

Charles University, Pharmaceutic Faculty, Dept. of Biological and Medical Sciences, Heyrovského 1203, 50005 Hradec Králové, Czech Republic

A propos de : Petr Nachtigal

Charles University, Pharmaceutic Faculty, Dept. of Biological and Medical Sciences, Heyrovského 1203, 50005 Hradec Králové, Czech Republic

A propos de : Kamila Langrová

Czech Technical University, Faculty of Mechanical Engineering, Department of Mathematics, Karlovo nám. 13, 121 35 Praha'2, Czech Republic

A propos de : Viktor Beneš

Czech Technical University, Faculty of Mechanical Engineering, Department of Mathematics, Karlovo nám. 13, 121 35 Praha'2, Czech Republic