Acta Stereologica

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Heinz David

Thirty years of experience in ultrastructural quantitative morphology and stereology of the liver

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Abstract

Against the background of the author’s own research results, an account is given of developments, over the past 30 years, in the use of quantitative methods in optical light and electron microscopy of the liver. The liver is used as an example to show that on top of the generally known methods of stereology additional, quantitative approaches, some of them in combination with each other, are necessary to characterise biological structures. Such approaches have been developed by the author, for example, to determine relationships between cell organelles, on the one hand, and specific bonding on the cell membrane, on the other, with microvilli being an example. Combination of quantitative results with qualitative assessment of cellular components is of decisive importance to cellular research and medical diagnosis, if conclusive findings are to be achieved.

To cite this article

Heinz David, «Thirty years of experience in ultrastructural quantitative morphology and stereology of the liver», Acta Stereologica [En ligne], Volume 6 (1987), Supplement II (The commemorative-memorial volume: twenty-five years of stereology) - May 1987, 203-211 URL : https://popups.ulg.ac.be/0351-580x/index.php?id=2274.

About: Heinz David

Humboldt University of Berlin, GDR, Charité School of Medicine, Institute of Pathology, Department of Ultrastructural Pathology and Electron Microscopy, Schumannstr. 20-21, Berlin, DDR-1040