Acta Stereologica Acta Stereologica -  Volume 11 (1992)  Number 2 - Dec. 1992 

Morphometrical changes in follicles of the thyroid glands in chronic alcoholism

Milica Matavulj
University of Regensburg, Institute of Anatomy, Universitätstr. 31, D-8400 Regensburg, Germany
Milan Kecman
Institute of Histology and Embryology, Faculty of Medicine, Novi Sad, Yugoslavia
Ljiljana Somer
Institute of Histology and Embryology, Faculty of Medicine, Novi Sad, Yugoslavia

Abstract

The effect of chronic ethanol consumption on the structure of thyroid gland follicles was the subject of our studies. Mature male Wistar rats were given 15% ethanol solution ad libitum as the only liquid offered. The animals were sacrificed in three groups: one, three and six months after the beginning of alcohol ingestion. Stereological analysis showed a significant increase in the volume density of follicular epithelium /Vve/, its thickness /t/, index of activation of the thyroid gland /Ia=Vve/Vvc/, and significant reduction in volume density of colloid /Vvc/ in all the periods examined. These results suggest the possibility that long-term alcoholism can disturb the normal structure of the thyroid gland, besides its well-known effects on the peripheral metabolism of thyroid hormones.

Keywords : chronic ingestion of ethanol, stereology, thyroid gland

To cite this article

Milica Matavulj, Milan Kecman & Ljiljana Somer, «Morphometrical changes in follicles of the thyroid glands in chronic alcoholism», Acta Stereologica [En ligne], Volume 11 (1992), Number 2 - Dec. 1992, 199-204 URL : https://popups.ulg.ac.be/0351-580x/index.php?id=1941.