Acta Stereologica

0351-580X

 

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Metka Logonder-Mlinšek

The influence of experimental hyperthyroidism and hypothyroidism on mouse bone tissue

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Abstract

The effect of L-thyroxine and sodium perchlorate on bone tissue in a 64-day long experiment was studied on 12 male mice. It was found that L-thyroxine caused a significant increase in the numerical areal density of osteoclasts and in the volume density of bone marrow cavities, while the volume density of mineralised bone was significantly decreased. The application of perchlorate caused a significant decrease in the numerical areal density of osteoclasts, in the volume density of bone marrow cavities and osteoid; the volume density of mineralised bone tissue was significantly increased in this condition.

Keywords : bone tissue, hyperthyroidism, hypothyroidism, mouse

To cite this article

Metka Logonder-Mlinšek, «The influence of experimental hyperthyroidism and hypothyroidism on mouse bone tissue», Acta Stereologica [En ligne], Volume 12 (1993), Number 1 - Sep. 1993, 59-63 URL : https://popups.ulg.ac.be/0351-580x/index.php?id=1397.

About: Metka Logonder-Mlinšek

Institute of Histology and Embryology, Faculty of Medicine, University in Ljubljana, Korytkova 2, 61105 Ljubljana, Slovenia