Acta Stereologica Acta Stereologica -  Volume 13 (1994)  Number 1 - Proceedings of the sixth European congress for stereology - Part two - May 1994 

The prognostic value of quantitative histopathology in breast cancer: results of retrospective studies

Morten Ladekarl
Stereological Research Laboratory, Bartholin Building, University of Aarhus, 8000 Aarhus C, Denmark
Flemming Brandt Sørensen
Stereological Research Laboratory, Bartholin Building, University of Aarhus, 8000 Aarhus C, Denmark

Abstract

The results of retrospective studies of breast cancer patients, regarding the prognostic value of quantitative histopathologic estimates, are summarized. The stereologic estimates of the volume-weighted mean volume of cancer cell nuclei were of independent prognostic value, both in breast cancers of the ductal and the lobular types. This variable is easily obtained from ordinary histologic sections, highly reproducible, and suitable for routine use. In addition, in breast carcinomas of the lobular type, estimates of the mitotic frequency were strong predictors of the prognosis.

Keywords : breast cancer, morphometry, nuclear volume, prognosis, stereology

To cite this article

Morten Ladekarl & Flemming Brandt Sørensen, «The prognostic value of quantitative histopathology in breast cancer: results of retrospective studies», Acta Stereologica [En ligne], Volume 13 (1994), Number 1 - Proceedings of the sixth European congress for stereology - Part two - May 1994, 69-74 URL : https://popups.ulg.ac.be/0351-580x/index.php?id=1016.